Bound Therapeutics Closes First Round of Pre-Seed Financing, Bringing Total Funding to $3.4M
June 14, 2019
RNA Blockade to Treat Triple Negative Breast Cancer
News
September 10, 2018
Bound Therapeutics is selected as a finalist in the UC Science Center QED proof-of-concept program
News
October 30, 2017
Bound Therapeutics formed strategic alliance with Bio-Synthesis, Inc. to jointly develop bridged nucleic acid (BNA)-based RNA therapeutics
News
December 12, 2015
Bound Therapeutics is featured in Genetic Engineering & Biotechnology News
News
Publications
Yuanyuan Jin, Vilas S Desai, Jason D Mazzaroth, Eric Wickstrom
IGF1R-targeted delivery of a bridged nucleic acid oligonucleotide-peptide conjugate for microRNA-21 inhibition in triple-negative breast cancer, NAR Cancer, Volume 7, Issue 4, December 2025
Tripathi, S. K., R. Kean, E. Bongiorno, D. C. Hooper, Y. Y. Jin, E. Wickstrom, P. A. McCue, and M. L. Thakur. (Apr 2020)
"Non-Specific Blocking of Mir-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity." PLoS One 10, no. 12: e0142574.
Wickstrom, E. (Jun 29 2015)
"DNA and Rna Derivatives to Optimize Distribution and Delivery." Adv Drug Deliv Rev 87 : 25-34.
Sonar, M. V., M. E. Wampole, Y. Y. Jin, C. P. Chen, M. L. Thakur, and E. Wickstrom. (Sep 17 2014)
"Fluorescence Detection of Kras2 Mrna Hybridization in Lung Cancer Cells with Pna- Peptides Containing an Internal Thiazole Orange." Bioconjug Chem 25, no. 9: 1697-708.
Sanders, J. M., M. E. Wampole, M. L. Thakur, and E. Wickstrom. (2013)
"Molecular Determinants of Epidermal Growth Factor Binding: A Molecular Dynamics Study." PLoS One 8, no. 1: e54136.
Sanders, J. M., M. E. Wampole, C. P. Chen, D. Sethi, A. Singh, F. Y. Dupradeau, F. Wang, B. D. Gray, M. L. Thakur, and E. Wickstrom. (Oct 3 2013)
"Ehects of Hypoxanthine Substitution in Peptide Nucleic Acids Targeting Kras2 Oncogenic Mrna Molecules: Theory and Experiment." J Phys Chem B 117, no. 39: 11584-95.
Paudyal, B., K. Zhang, C. P. Chen, M. E. Wampole, N. Mehta, E. P. Mitchell, B. D. Gray, J. A. Mattis, K. Y. Pak, M. L. Thakur, and E. Wickstrom. (Nov 2013)
"Determining Ehicacy of Breast Cancer Therapy by Pet Imaging of Her2 Mrna." Nucl Med Biol 40, no. 8: 994-9.
Sethi, D., C. P. Chen, R. Y. Jing, M. L. Thakur, and E. Wickstrom. (Feb 15 2012)
"Fluorescent Peptide-Pna Chimeras for Imaging Monoamine Oxidase a Mrna in Neuronal Cells." Bioconjug Chem 23, no. 2: 158-63.
Amirkhanov, N. V., K. Zhang, M. R. Aruva, M. L. Thakur, and E. Wickstrom. (Apr 21 2010)
"Imaging Human Pancreatic Cancer Xenografts by Targeting Mutant Kras2 Mrna with [(111)in]Dota(N)- Poly(Diamidopropanoyl)(M)-Kras2 Pna-D(Cys-Ser-Lys-Cys) Nanoparticles." Bioconjug Chem 21, no. 4: 731-40.
Tian, X., M. R. Aruva, K. Zhang, N. Shanthly, C. A. Cardi, M. L. Thakur, and E. Wickstrom. (Oct 2007)
"Pet Imaging of Ccnd1 Mrna in Human Mcf7 Estrogen Receptor Positive Breast Cancer Xenografts with Oncogene-Specific [64cu]Chelator-Peptide Nucleic Acid- Igf1 Analog Radiohybridization Probes." J Nucl Med 48, no. 10: 1699-707.
Cesarone, G., O. P. Edupuganti, C. P. Chen, and E. Wickstrom. no. 6 (Nov-Dec 2007)
"Insulin Receptor Substrate 1 Knockdown in Human Mcf7 Er+ Breast Cancer Cells by Nuclease-Resistant Irs1 Sirna Conjugated to a Disulfide-Bridged D-Peptide Analogue of Insulin-Like Growth Factor 1." Bioconjug Chem 18, no. 6: 1831-40.
Events & Presentations
April 15, 2024
Festival of Biologics
October 22, 2023
The Oligonucleotide Therapeutics Society
Event
October 8, 2017
Advances in Breast Cancer Research at American Association for Cancer Research
