Bound Therapeutics | News

Press Release

June 14, 2019

RNA Blockade to Treat Triple Negative Breast Cancer

News
September 10, 2018

Bound Therapeutics is selected as a finalist in the UC Science Center QED proof-of-concept program

News
October 30, 2017

Bound Therapeutics formed strategic alliance with Bio-Synthesis, Inc. to jointly develop bridged nucleic acid (BNA)-based RNA therapeutics

News
December 12, 2015

Bound Therapeutics is featured in Genetic Engineering & Biotechnology News

News

Publications

Tripathi, S. K., R. Kean, E. Bongiorno, D. C. Hooper, Y. Y. Jin, E. Wickstrom, P. A. McCue, and M. L. Thakur. (Apr 2020)
"Targeting Vpac1 Receptors for Imaging Glioblastoma." Mol Imaging Biol 22, no. 2: 293-302.
Oh, E., Y. Liu, M. V. Sonar, D. E. Merry, and E. Wickstrom. (Apr 18 2018)
"Fluorescence Imaging of Huntingtin Mrna Knockdown." Bioconjug Chem 29, no. 4: 1276-82.
Jin, Y. Y., J. Andrade, and E. Wickstrom. (2015)
"Non-Specific Blocking of Mir-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity." PLoS One 10, no. 12: e0142574.
"DNA and Rna Derivatives to Optimize Distribution and Delivery." Adv Drug Deliv Rev 87 : 25-34.
Sonar, M. V., M. E. Wampole, Y. Y. Jin, C. P. Chen, M. L. Thakur, and E. Wickstrom. (Sep 17 2014)
"Fluorescence Detection of Kras2 Mrna Hybridization in Lung Cancer Cells with Pna- Peptides Containing an Internal Thiazole Orange." Bioconjug Chem 25, no. 9: 1697-708.
Sanders, J. M., M. E. Wampole, M. L. Thakur, and E. Wickstrom. (2013)
"Molecular Determinants of Epidermal Growth Factor Binding: A Molecular Dynamics Study." PLoS One 8, no. 1: e54136.
Sanders, J. M., M. E. Wampole, C. P. Chen, D. Sethi, A. Singh, F. Y. Dupradeau, F. Wang, B. D. Gray, M. L. Thakur, and E. Wickstrom. (Oct 3 2013)
"Ehects of Hypoxanthine Substitution in Peptide Nucleic Acids Targeting Kras2 Oncogenic Mrna Molecules: Theory and Experiment." J Phys Chem B 117, no. 39: 11584-95.
Paudyal, B., K. Zhang, C. P. Chen, M. E. Wampole, N. Mehta, E. P. Mitchell, B. D. Gray, J. A. Mattis, K. Y. Pak, M. L. Thakur, and E. Wickstrom. (Nov 2013)
"Determining Ehicacy of Breast Cancer Therapy by Pet Imaging of Her2 Mrna." Nucl Med Biol 40, no. 8: 994-9.
Sethi, D., C. P. Chen, R. Y. Jing, M. L. Thakur, and E. Wickstrom. (Feb 15 2012)
"Fluorescent Peptide-Pna Chimeras for Imaging Monoamine Oxidase a Mrna in Neuronal Cells." Bioconjug Chem 23, no. 2: 158-63.
Amirkhanov, N. V., K. Zhang, M. R. Aruva, M. L. Thakur, and E. Wickstrom. (Apr 21 2010)
"Imaging Human Pancreatic Cancer Xenografts by Targeting Mutant Kras2 Mrna with [(111)in]Dota(N)- Poly(Diamidopropanoyl)(M)-Kras2 Pna-D(Cys-Ser-Lys-Cys) Nanoparticles." Bioconjug Chem 21, no. 4: 731-40.
Tian, X., M. R. Aruva, K. Zhang, N. Shanthly, C. A. Cardi, M. L. Thakur, and E. Wickstrom. (Oct 2007)
"Pet Imaging of Ccnd1 Mrna in Human Mcf7 Estrogen Receptor Positive Breast Cancer Xenografts with Oncogene-Specific [64cu]Chelator-Peptide Nucleic Acid- Igf1 Analog Radiohybridization Probes." J Nucl Med 48, no. 10: 1699-707.
Cesarone, G., O. P. Edupuganti, C. P. Chen, and E. Wickstrom. no. 6 (Nov-Dec 2007)
"Insulin Receptor Substrate 1 Knockdown in Human Mcf7 Er+ Breast Cancer Cells by Nuclease-Resistant Irs1 Sirna Conjugated to a Disulfide-Bridged D-Peptide Analogue of Insulin-Like Growth Factor 1." Bioconjug Chem 18, no. 6: 1831-40.

Events & Presentations

October 22, 2023
The Oligonucleotide Therapeutics Society
Event
October 8, 2017
Advances in Breast Cancer Research at American Association for Cancer Research
Event
September 5, 2017
Nucleic Acids Chemistry & Biology 7th Cambridge Symposium
Event
August 24, 2016
252nd American Chemical Society National Meeting
Event
July 22, 2016
XXII International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
Event
August 29, 2014
Regulatory & Non-coding RNAs at Cold Spring Harbor Laboratory
Event